objective: methanol extract of bran and unpolished grain of two traditional aromatic rice genotypes viz. kalijira and chinigura were assayed for their activity on the growth and initiation of crown-gall tumors on potato disks. materials and methods: three agrobacterium tumefaciens (a. tumefaciens) strain atsl0105, atta0112, and atac0114 were used as the tumor forming agent. collected rice was s...

different acid chlorides (2a-d) reacted with anthranilic acid to produce 2-substituted-3, 1-benzoxazin-4-one (3a-d) which was used as starting material to synthesize some condensed and non-condensed heterocyclic compounds by reaction with nitrogen nucleophiles e.g., hydrazine hydrate, and formamide. some of the newly synthesized analogues were chosen to evaluate their cytotoxic activity against...

ft-sers (fourier transform surface enhanced raman scattering) of adriamycin and its complex with dna is reported. it is shown that in agreement with previous raman studies the interaction of adriamycin  with dna takes place through an intercalation mechanism. the presence of a new band at 731 cm-1 suggests that ring d of adriamycin is not involved in the intercalation process.

paris polyphylla smith var. yunnanensis, has been used in traditional chinese medicine for its antibiotic and anti-inflammatory properties; in addition it has been used to cure liver cancer in particular. in this current study, β-ecdysterone (1) and three pennogenin steroidal saponins (2-4) were isolated from the etoh extract of paris polyphylla var. yunnanensis, and then tested for their antit...

synthesis, characterization, spectral and theoretical calculations of sodium tetrafluoroborate (iii) (stfb) has been studied in this research. sodium tetrafluoroborate (iii) was synthesized by a sonochemical method and characterized by ir, uv/vis, 11b-nmr and mass spectrometer techniques. the nano compound was characterized by scanning electron microscopy (sem), x-ray powder diffraction (xrd) a...

Epithelial Ovarian cancer is the leading cause of cancer mortality among women all over the world. As chemotherapeutics has many side effects, researchers have focused on the potential use of medicinal plants as natural antitumor agents. Xanthium strumarium studied in this work as an herbal anticancer agent. This study aimed to evaluate the antitumor effect and metabolic alterations ca...

attempts have been made to prepare nanoparticles based on poly(lactic-co-glycolic acid) (plga) and doxorubicin. biological evaluation and physio-chemical characterizations were performed to elucidate the effects of initial drug loading and polymer composition on nanoparticle properties and its antitumor activity. plga nanoparticles were formulated by sonication method. lactide/glycolide ratio a...

The antitumor activity of ethanol extract of Prosopis glandulosa Torr. (EPG) was evaluated against Ehrlich ascites carcinoma (EAC) tumor model in Swiss albino mice on dose dependent manner. The activity was assessed using survival time, average increase in body weight, hematological parameters and solid tumor volume. Oral administration of EPG at the dose of 100, 200 and 400 mg/Kg, significantl...

the antitumor activity of ethanol extract of prosopis glandulosa torr. (epg) was evaluated against ehrlich ascites carcinoma (eac) tumor model in swiss albino mice on dose dependent manner. the activity was assessed using survival time, average increase in body weight, hematological parameters and solid tumor volume. oral administration of epg at the dose of 100, 200 and 400 mg/kg, significantl...